Listerine® Antiseptic Mouthwash being poured on a tooth to Attack Plaque from every angle.

RESEARCH REVEALS

LISTERINE^® ANTISEPTIC IS 4.6X MORE EFFECTIVE
THAN FLOSS FOR SUSTAINED
PLAQUE REDUCTION
ABOVE THE GUMLINE*

*Flossing by a dental hygienist. Sustained plaque reduction after dental prophylaxis.

The Scientific Evidence

STUDY DESIGN

NEW: A 12-WEEK STUDY REVEALS EXCITING DATA ON THE BENEFITS OF LISTERINE® ANTISEPTIC¹

For any patient — regardless of their flossing habits — LISTERINE® Antiseptic can help manage oral health.

LISTERINE® chart for a clinical study result including a percentage Reduction in Interproximal Turesky Plaque Index at 12 Weeks

LISTERINE® chart for a clinical study result including a percentage Reduction in Interproximal MGI Index at 12 Weeks

LISTERINE® chart for a clinical study result including a percentage Reduction in Interproximal Bleeding Index at 12 Weeks

STUDY DESIGNTHE NEW 12-WEEK STUDY OF LISTERINE^® ANTISEPTIC AND FLOSSING IS AVAILABLE NOW

A CLOSER LOOK INTO THE SCIENCE BEHIND LISTERINE^® ANTISEPTIC

LISTERINE® Antiseptic | 4.6x Greater Supragingival Plaque Reduction Than Flossing

THE POWER OF LISTERINE^®

Discover what makes LISTERINE® Antiseptic more effective than floss against plaque above the gumline.

Disclaimer: This is a US video with US product images.

MORE ABOUT LISTERINE® AND ORAL HEALTH

Decades of Clinical Proof

Learn how LISTERINE® Antiseptic became the #1 recommended brand by dentists and hygienists.*

*Based on 2021 Oral Tracking survey of 190 dentists and 190 hygienists.

How LISTERINE® Antiseptic tackles the Oral Microbiome to keep it balanced.

Dispel myths about alcohol-containing mouthrinses.

See the benefits or flossing as part of a comprehensive oral health regimen.

A COMPREHENSIVE APPROACH TO DAILY ORAL CARE

Together, brushing, flossing, and rinsing with LISTERINE® Antiseptic on a daily basis provides a comprehensive approach to oral care and an approach to cleaning that reaches nearly 100% of the mouth.^2,3

BRUSHING

Removes plaque and debris from tooth surfaces.

FLOSSING

Reaches below the gumline and removes imbedded food particles and plaque between the teeth⁴

LISTERINE® ANTISEPTIC

Uses an antimicrobial mechanism of action to help prevent plaque buildup above the gumline.^5-7

References: 1. Bosma ML, McGuire JA, Sunkara A, Sullivan P, Yoder A, Milleman J, Milleman K. Efficacy of Flossing and Mouthrinsing Regimens on Plaque and Gingivitis: A randomized clinical trial. J Dent Hyg. June 2022; 96(3), 8-20. 2. Recognized Products. Canadian Dental Association website. http://www.cda-adc.ca/EN/oral_health/seal/products/product_page.asp?prod... Last reviewed July 22, 2020. Accessed January 3, 2022. 3. Kerr WJS, Kelly J, Geddes DAM. The areas of various surfaces in the human mouth from nine years to adulthood. J Dent Res. 1991;70(12):1528-1530. 4. Flossing & Brushing. Canadian Dental Association website. https://www.cda-adc.ca/en/oral_health/cfyt/dental_care/flossing_brushing... Last reviewed September 21, 2021. Accessed January 3, 2022. 5. Fine DH, Letizia J, Mandel ID. The effect of rinsing with Listerine’ antiseptic on the properties of developing dental plaque. J Clin Periodontol. 1985;12(8):660-666. 6. Kubert D, Rubin M, Barnett ML, Vincent JW. Antiseptic mouthrinse-induced microbial cell surface alterations. Am J Dent. 1993;6(6):277-279. 7. Pan P, Barnett ML, Coelho J, Brogdon C, Finnegan MB. Determination of the in situ bactericidal activity of an essential oil mouthrinse using a vital stain method. J Clin Periodontol. 2000;27(4):256-261. 8. Pitts G, Pianotti R, Feary TW, McGuiness J, Masurat T. The in vivo effects of an antiseptic mouthwash on odor-producing microorganisms. J Dent Res. 1981;60(11):1891-1896. 9. Pitts G, Brogdon L, Hu L, Masurat T, Pianotti R, Schumann P. Mechanism of action of an antiseptic, anti-odor mouthwash. J Dent Res. 1983;62(6):738-742. 10. Ilg D, McGuire JA, Mordas CJ, Queiroz D, Fourre T, Santos SL. In vitro efficacy of an alcohol-free essential oil containing mouthrinse. J Dent Hyg. 2012;86(1):50-51.